The small size of the silver nanoparticles is a key advantage that allows the nanoparticles and the released silver ions to penetrate the cell walls of the virus. The size of silver nanoparticles ranges from 1 to 100 nm, which makes them very effective in interacting with microorganisms. The average size of the virus fluctuates between 30-150 nm, bacteria 300-50,000 and fungi> 2,000. Coronavirus, on the other hand, has the shape of a sphere with a diameter of about 130 nm, the smallest units are about 60 nm and it is their size that allows the penetration of silver nanoparticles into the Coronavirus, largely reducing its effect. Scientists have shown that the antimicrobial activity of silver nanoparticles is mainly due to the sustained release of free silver ions from the nanoparticles that carry them. The silver ions are positively charged and absorbed by the negatively charged surface of the bacteria. After passing through the membrane of the microorganism, they inhibit respiratory functions, cell division and replication processes, ultimately eliminating the microorganism. Silver ions can bind to the RNA DNA of viruses such as HIV, RSV, and SARS and effectively render them inert. The already destroyed microorganism is then naturally discarded, while the silver nanoparticles continue to act on other viruses, bacteria or fungi.